Nasal Spray Prochlorperazine migraine treatment

Researchers at the Roseman University of Health Sciences in the USA believe that prochlorperazine, an anti-nausea medication already available in tablet and injection form, could provide better pain relief than other medications currently used to treat migraine symptoms. They suggest that a nasal spray version of prochlorperazine would not only be effective, but fast acting and more patient-friendly as nasal sprays tend to have fewer side effects than oral alternatives. Prochlorperazine is a dopamine receptor antagonist that is widely used as an anti-nausea medication. Comparative clinical studies have shown that prochlorperazine provides better pain relief than other anti-migraine drugs. Currently, there are no marketed nasal spray formulations of prochlorperazine available for the treatment of migraine. Prochlorperazine is available in tablet form, which has delayed onset of action